Arctium lappa Lam. and Its Related Lignans Improve Hyperglycemia and Dyslipidemia in Diabetic Rodent Models: A Systematic Review and Meta-Analysis

Research on nutraceuticals has focused reducing the onset, progression, and significant consequences of diabetes mellitus. Arctium lappa Lam. is a great source plant fibers polyphenols that have anti-disease benefits, including those for This study sought to determine impact extracts its associated lignans diabetic hyperglycemia dyslipidemia by conducting meta-analyses available research using rodents. English-language peer-reviewed articles were searched PubMed Embase up until 10 August 2022. Included studies comparing blood glucose and/or lipid levels rodents given either related or vehicles. Blood reported in 16 involving 168 mice rats treated with controls. The pooled effect size was −1.42 [95% CI: −1.84 −1.00] heterogeneity. Type model found be prominent covariate explained, at least partially, Moreover, showed notable improvement their hypertriglyceridemia hypercholesterolemia.